India Today Group Online
 


June 11, 2001
Issue


 

COVER
   

Syndrome X
Studies show that Indians are genetically predisposed to physiological symptoms collectively called Syndrome X. This makes them highly susceptible to heart disease. Fortunately, technology can help detect coronary artery disease at an early stage.

 

 
THE NATION
   

Peace By Piece
Having failed to make headway with the cease-fire, the Centre is now trying to talk peace on Kashmir, internally through its negotiator K.C. Pant and externally with Pakistan's Chief Executive General Pervez Musharraf. But will anything come out of this?

 

 
ECONOMY
 

Good Monsoon
So What?
The traditional link between the monsoon and the economy weakens.

 

 
INVESTIGATION
 

Slippery Deal
The ONGC subsidiary's whopping Rs 8,136 crore investment was signed in indecent haste.

 

 
OTHER STORIES
     
 



 
  Home  
 

PROFILE: KALLAM ANJI REDDY

Doctor Yes

By the sheer spirit of innovation and research, a scientist from the private sector has authored an international success story worth Rs 800 crore

This is about a different kind of drug addict. For, the addiction of Dr Kallam Anji Reddy may turn out to be the liberation of millions. And, here in this dim-lit room in Hyderabad, he is waiting for that distant day, the day when "made-in-India drugs of international quality will be available over the counter around the globe". That will be the day of his ultimate high, or, in his own soft-spoken words, "spiritual enlightenment". Actually, the day is not so distant.

Please note: Reddy, 61, doesn't take drugs, he makes them. Today, the founder-chairman of Dr Reddy's Laboratories (DRL), Hyderabad, is India's first scientist, that too from the private sector, who has made it big in the international marketplace. He has just sold the first in a new class of anti-diabetes molecules called insulin sensitisers to the Swiss multinational Novartis Pharma AG for $55 million (Rs 258 crore). The multinational giant will also have the rights to develop and market the drug. "It is a significant event in our evolution as a research-oriented pharmaceutical company," says Reddy, who at the moment seems to be excited more by the name of the buyer than by the price.

If Reddy's drug is worth the money, by 2007, some 140 million afflicted with Type 2 diabetes will be the beneficiaries. Dr Reddy's Research Foundation (DRF), the R&D arm set up in 1993 to take up frontline research, has already sold two anti-diabetic molecules to the Danish firm Novo Nordisk in 1997 and 1998 for $8 million. And Reddy's current obsession is a drug that reduces bad cholesterol and triglycerides and elevates HDL or good, beneficial cholesterol. That will be a revolutionary moment, for there is no effective drug for metabolic disorders. Once it is cleared after clinical trials in Europe, Reddy plans to produce the drug by himself. Negotiations consume so much time, and he has other products in mind, including two for the treatment of cancer.

Reddy has just sold the first in a revolutionary class of anti-diabetes molecules to Novartis for $55 million (Rs 258 crore).

This is a unique evolutionary tale in Indian science. The can-do determination of one man, that too from outside the official scientific establishment, has become the finest moment in Indian R&D. The achievement is all the more important because biotechnology is the happening area in science today. The man himself remains modest: "I did not even in the wildest of dreams imagine that I would come this far." Perhaps it was inevitable. "He was talking about R&D when it was not fashionable to do so. He is a perfect role model," says Sandhya Tewari, deputy director, Confederation of Indian Industry.

True, there were no takers when Reddy, a scientist with no foreign qualifications (graduation in pharmaceutical science and technology from the Bombay University, doctorate from the National Chemical Laboratory in Pune) advocated the Japanese model of advancement of basic research and of upgrading industry to invent new molecules for development way back in 1993. He was then delivering the presidential address at the Bangalore session of the Indian Pharmaceutical Congress.

DRF is a vindication of his argument. An investment of Rs 111.75 crore in eight years has led to its researchers filing for 55 US patents, of which 19 have already been granted. No mean achievement, for the best of pharma companies in India have not secured more than nine patents after investing $20 million in research.

His stint at the state-owned Indian Drugs and Pharmaceuticals Limited has helped Reddy switch his business strategies. In the beginning, like others in the industry, he copied liberally, taking full advantage of the government's policy of rejecting international patents and allowing companies to produce generic drugs. But he realised that by 2005, under the WTO agreement, product patents would be recognised in India.

So, relying on experience, Reddy staggered the research schedule to focus first on "anologues" that are marginally different versions of existing drugs. Then he moved on to the new class of insulin sensitisers and finally began work with a compact but competent team of molecular biologists at the research centre in Atlanta, US, in July 2000. His direction for corporate R&D enabled DRL to achieve through its own research what no other company has done in this country. The Indian Space Research Organisation, though state controlled, is the only other scientific organisation that has shown some staying power. DRL's turnover in 1985, one year after its inception, was Rs 1.5 crore. Today it is Rs 800 crore.

But that has not changed Reddy's lifestyle. The son of a turmeric farmer from Guntur is a low-profile innovator. "The passion for discovery and innovation for a healthier life is what keeps me going. It is my real drive." Reddy has delegated manufacturing responsibilities to son Satish Reddy and son-in-law G.V. Prasad so that he can concentrate more on research, though DRF has a Harvard-returned chemist Dr A. Venkateswarlu as its president. "Clarity in thinking, a time-targeted approach and easy access are the attributes of his leadership," says DRL's corporate affairs head D. Ravi Rao.

Significantly, all but one of DRL's production units in India are in Reddy's home state. And politics is a big no. "I treat it as a source of great amusement because if I take it seriously I have to hang my head in shame."

For him, life is all about opportunities. That is why he is an enemy of child labour. He has started the Livelihood Advancement Business Schools as an answer to this social injustice. "We are doing this in a sustained manner instead of looking it as charity. If a few thousand of us can do this much to educate disadvantaged children, they will learn to pull themselves out of the poverty trap," says Reddy. Any regrets? "Time appears to be moving fast. Sometimes I feel I am going up in an escalator all the time." Maybe he is, to reach new heights. For a man who once envied the Bose speaker for being the only world-class product with an Indian name, the journey is a prelude to bigger Reddy days, R&D days.

Today, Reddy is wearing a new pair of spectacles on the advice of a photographer that makes him more camera friendly. Going by the limelight, the doctor may need more pairs.


 
 
 



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